Tae-Sik Park Selected Research

Sphingomyelins

1/2022	De Novo Sphingolipid Biosynthesis in Atherosclerosis.
7/2021	Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease.
11/2020	Circulating lipidomic alterations in obese and non-obese subjects with non-alcoholic fatty liver disease.
12/2016	Liver serine palmitoyltransferase activity deficiency in early life impairs adherens junctions and promotes tumorigenesis.
10/2011	Reducing plasma membrane sphingomyelin increases insulin sensitivity.
4/2009	Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.
12/2006	Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice.
11/2004	Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice.

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Tae-Sik Park Research Topics

Disease

12	Insulin Resistance 01/2022 - 03/2009
11	Atherosclerosis 01/2022 - 11/2004
7	Obesity 05/2020 - 06/2007
6	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2017
6	Cardiomyopathies (Cardiomyopathy) 01/2014 - 06/2007
6	Heart Failure 01/2014 - 06/2007
4	Neoplasms (Cancer) 01/2022 - 03/2013
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 03/2009
4	Hyperglycemia 08/2020 - 03/2009
4	Fatty Liver 05/2020 - 11/2012
4	Body Weight (Weight, Body) 01/2020 - 02/2009
4	Inflammation (Inflammations) 01/2020 - 01/2013
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 07/2008
2	Atherosclerotic Plaque (Atheroma) 07/2021 - 07/2008
2	Fibrosis (Cirrhosis) 05/2020 - 01/2017
2	Metabolic Diseases (Metabolic Disease) 05/2020 - 10/2017
2	Liver Diseases (Liver Disease) 05/2020 - 01/2013
2	Glucose Intolerance 05/2020 - 07/2015
2	Colitis 01/2019 - 11/2018
2	Hepatocellular Carcinoma (Hepatoma) 03/2017 - 01/2013
2	Coronary Disease (Coronary Heart Disease) 12/2006 - 11/2004
1	Infections 05/2020
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2020
1	Erythema 01/2020
1	Colorectal Neoplasms (Colorectal Cancer) 05/2019
1	Immune System Diseases (Immune Disorders) 01/2019
1	Diarrhea 11/2018
1	Allergic Contact Dermatitis 11/2018
1	Lipodystrophy 10/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017
1	Jaundice (Icterus) 12/2016
1	Carcinogenesis 12/2016
1	Neointima 07/2015
1	Lung Diseases (Lung Disease) 10/2014
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 07/2013

Drug/Important Bio-Agent (IBA)

13	SphingolipidsIBA 01/2022 - 12/2006
12	LipidsIBA 11/2020 - 06/2007
9	CeramidesIBA 01/2022 - 10/2008
8	SphingomyelinsIBA 01/2022 - 11/2004
7	Glucose (Dextrose)FDA LinkGeneric 08/2020 - 02/2009
6	Insulin (Novolin)FDA Link 01/2022 - 03/2009
6	CholesterolIBA 01/2020 - 11/2004
5	Serine C-PalmitoyltransferaseIBA 01/2022 - 07/2008
5	Triglycerides (Triacylglycerol)IBA 11/2020 - 02/2009
4	EnzymesIBA 01/2020 - 02/2009
3	CytokinesIBA 12/2021 - 01/2013
2	phosphatidylcholine-ceramide phosphocholine transferaseIBA 01/2022 - 07/2012
2	Bile Acids and Salts (Bile Acids)IBA 12/2021 - 01/2013
2	Biomarkers (Surrogate Marker)IBA 12/2021 - 11/2020
2	DiglyceridesIBA 11/2020 - 03/2009
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 05/2020 - 01/2020
2	Pyruvic Acid (Pyruvate)IBA 05/2020 - 10/2016
2	JNK Mitogen-Activated Protein KinasesIBA 05/2020 - 06/2011
2	Insulin Receptor Substrate ProteinsIBA 05/2020 - 06/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2019 - 07/2013
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2019 - 11/2018
2	Dextrans (Dextran)FDA Link 01/2019 - 11/2018
2	Sirtuin 1IBA 12/2018 - 01/2014
2	Nicotine FDA Link 01/2018 - 10/2014
2	AntioxidantsIBA 01/2018 - 01/2017
2	Fatty Acids (Saturated Fatty Acids)IBA 05/2012 - 06/2011
2	Apolipoproteins E (ApoE)IBA 04/2009 - 07/2008
2	thermozymocidin (myriocin)IBA 04/2009 - 07/2008
2	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 10/2008 - 09/2008
1	indoleIBA 12/2021
1	Tryptophan (L-Tryptophan)FDA Link 12/2021
1	Sphingosine-1-Phosphate ReceptorsIBA 07/2021
1	GlycosphingolipidsIBA 07/2021
1	AcidsIBA 05/2020
1	Serine (L-Serine)FDA Link 05/2020
1	LyasesIBA 01/2020
1	Imiquimod (Aldara)FDA LinkGeneric 01/2020
1	16S Ribosomal RNAIBA 01/2020
1	AdiponectinIBA 01/2019
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2018
1	sphingosine 1-phosphate lyase (aldolase)IBA 11/2018
1	DinitrofluorobenzeneIBA 11/2018
1	naringinIBA 01/2018
1	Dihydrotachysterol (AT 10)IBA 01/2018
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 03/2017
1	Celecoxib (Celebrex)FDA Link 03/2017
1	FructoseIBA 01/2017
1	Glutathione (Reduced Glutathione)IBA 01/2017
1	NADP (NADPH)IBA 01/2017
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2017
1	AlbuminsIBA 12/2016
1	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 10/2016
1	Malonyl Coenzyme A (Malonyl CoA)IBA 10/2016
1	Tricarboxylic AcidsIBA 10/2016
1	sphingosine kinaseIBA 07/2015
1	Acyl Coenzyme A (Acyl CoA)IBA 01/2014
1	beta-lapachoneIBA 01/2014
1	EndocannabinoidsIBA 07/2013
1	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 07/2013
1	Pharmaceutical PreparationsIBA 03/2013

Therapy/Procedure

3	Therapeutics 12/2021 - 08/2004
3	Oral Administration 11/2018 - 04/2009
1	Radiotherapy 05/2019
1	Hepatectomy 12/2016